One of the gut-ripping, walking the floor at 2am is the shame that often pops up with The Disquiet. Dr. Brown has done important research around this. Shame is tied to being vulnerable, the very last thing most of us wants to be when in the midst of this experience.
This sense of shame is often associated with the crisis that comes with questioning the very things that brought success that feel empty, or the feeling of being out of step with the world are important forces that cause problems when ignored.
If this resonates, check out her other videos and books. While her major focus is working issues of shame with women, she makes some important distinctions that are useful here. In other videos, she makes some interesting comaprisons of how men and women deal with shame differently.
Dr Brene Brown on shame and vulnerability